A structural equation model to examine the clinical features of mild-to-moderate COVID-19: A multicenter Italian study.
Identifieur interne : 001798 ( Main/Exploration ); précédent : 001797; suivant : 001799A structural equation model to examine the clinical features of mild-to-moderate COVID-19: A multicenter Italian study.
Auteurs : Maria Rosaria Barillari [Italie, France] ; Luca Bastiani [Italie] ; Jerome R. Lechien [France] ; Giuditta Mannelli [France, Italie] ; Gabriele Molteni [France, Italie] ; Giovanna Cantarella [France, Italie] ; Nicola Coppola [Italie] ; Giuseppe Costa [Italie] ; Eleonora M C. Trecca [Italie] ; Calogero Grillo [Italie] ; Ignazio La Mantia [Italie] ; Carlos M. Chiesa-Estomba [France, Espagne] ; Claudio Vicini [Italie] ; Sven Saussez [France, Belgique] ; Andrea Nacci [France, Italie] ; Giovanni Cammaroto [France, Italie]Source :
- Journal of medical virology [ 1096-9071 ] ; 2020.
Abstract
The purpose of this study was to evaluate the clinical features of mild-to-moderate coronavirus disease 2019 (COVID-19) in a sample of Italian patients and to investigate the occurrence of smell and taste disorders. Infected individuals with suspected (clinical diagnosis) or laboratory-confirmed COVID-19 infection were recruited. Patients completed a survey-based questionnaire with the aim of assessing their epidemiological and clinical characteristics, general otorhinolaryngological symptoms, and smell and taste disorders. A total of 294 patients with mild-to-moderate COVID-19 completed the survey (147 females). The most prevalent general symptoms included fever, myalgia, cough, and headache. A total of 70.4% and 59.2% of patients reported smell and taste disorders, respectively. A significant association between the two above-mentioned disorders was found (rs: 0.412; P < .001). Smell disorders occurred before the other symptoms in 11.6% of patients and was not significantly associated with nasal obstruction or rhinorrhea. Interestingly, our statistical analysis did not show any significant difference, either for general symptoms or otorhinolaryngological features, between the clinical diagnosis group and the laboratory-confirmed diagnosis (polymerase chain reaction) group. The structural equation model confirmed significant standardized paths (P < .05) between general symptoms, comorbidities, and general otorhinolaryngological complaints in the absence of a significant correlation between these elements and smell and taste alterations. The prevalence of smell and taste disorders in mild-to-moderate Italian COVID-19 patients is significant both in suspected and laboratory-confirmed cases and reveals a strong correlation between these clinical signs regardless of the presence of general or otorhinolaryngological symptoms, such as nasal obstruction or rhinorrhea.
DOI: 10.1002/jmv.26354
PubMed: 32710639
Affiliations:
- Belgique, Espagne, France, Italie
- Lombardie, Région de Bruxelles-Capitale, Toscane, Île-de-France
- Bruxelles, Milan, Paris, Pise
- Université de Pise, Université libre de Bruxelles
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type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Otorhinolaryngology Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University Hospital AOUI Borgo Trento, University of Verona, Verona, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Otorhinolaryngology Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University Hospital AOUI Borgo Trento, University of Verona, Verona</wicri:regionArea><wicri:noRegion>Verona</wicri:noRegion></affiliation></author><author><name sortKey="Cantarella, Giovanna" sort="Cantarella, Giovanna" uniqKey="Cantarella G" first="Giovanna" last="Cantarella">Giovanna Cantarella</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Sciences and Community Health, Milan University, Milan University, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Community Health, Milan University, Milan University, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Otolaryngology, Fondazione IRCCS Ca' Granda Policlinico Hospital, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology, Fondazione IRCCS Ca' Granda Policlinico Hospital, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Coppola, Nicola" sort="Coppola, Nicola" uniqKey="Coppola N" first="Nicola" last="Coppola">Nicola Coppola</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Costa, Giuseppe" sort="Costa, Giuseppe" uniqKey="Costa G" first="Giuseppe" last="Costa">Giuseppe Costa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Trecca, Eleonora M C" sort="Trecca, Eleonora M C" uniqKey="Trecca E" first="Eleonora M C" last="Trecca">Eleonora M C. Trecca</name><affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia</wicri:regionArea><wicri:noRegion>Foggia</wicri:noRegion></affiliation></author><author><name sortKey="Grillo, Calogero" sort="Grillo, Calogero" uniqKey="Grillo C" first="Calogero" last="Grillo">Calogero Grillo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="La Mantia, Ignazio" sort="La Mantia, Ignazio" uniqKey="La Mantia I" first="Ignazio" last="La Mantia">Ignazio La Mantia</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Chiesa Estomba, Carlos M" sort="Chiesa Estomba, Carlos M" uniqKey="Chiesa Estomba C" first="Carlos M" last="Chiesa-Estomba">Carlos M. Chiesa-Estomba</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Universitario Donostia, San Sebastian, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Universitario Donostia, San Sebastian</wicri:regionArea><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Vicini, Claudio" sort="Vicini, Claudio" uniqKey="Vicini C" first="Claudio" last="Vicini">Claudio Vicini</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Otolaryngology, University of Ferrara, Ferrara, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Otolaryngology, University of Ferrara, Ferrara</wicri:regionArea><wicri:noRegion>Ferrara</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì</wicri:regionArea><wicri:noRegion>Forlì</wicri:noRegion></affiliation></author><author><name sortKey="Saussez, Sven" sort="Saussez, Sven" uniqKey="Saussez S" first="Sven" last="Saussez">Sven Saussez</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Nacci, Andrea" sort="Nacci, Andrea" uniqKey="Nacci A" first="Andrea" last="Nacci">Andrea Nacci</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>ENT Audiology Phoniatric Unit, University of Pisa, Pisa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>ENT Audiology Phoniatric Unit, University of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Cammaroto, Giovanni" sort="Cammaroto, Giovanni" uniqKey="Cammaroto G" first="Giovanni" last="Cammaroto">Giovanni Cammaroto</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì</wicri:regionArea><wicri:noRegion>Forlì</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32710639</idno><idno type="pmid">32710639</idno><idno type="doi">10.1002/jmv.26354</idno><idno type="wicri:Area/Main/Corpus">000843</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000843</idno><idno type="wicri:Area/Main/Curation">000843</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000843</idno><idno type="wicri:Area/Main/Exploration">000843</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A structural equation model to examine the clinical features of mild-to-moderate COVID-19: A multicenter Italian study.</title><author><name sortKey="Barillari, Maria Rosaria" sort="Barillari, Maria Rosaria" uniqKey="Barillari M" first="Maria Rosaria" last="Barillari">Maria Rosaria Barillari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Bastiani, Luca" sort="Bastiani, Luca" uniqKey="Bastiani L" first="Luca" last="Bastiani">Luca Bastiani</name><affiliation wicri:level="3"><nlm:affiliation>CNR Institute of Clinical Physiology, Pisa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>CNR Institute of Clinical Physiology, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region></placeName></affiliation></author><author><name sortKey="Lechien, Jerome R" sort="Lechien, Jerome R" uniqKey="Lechien J" first="Jerome R" last="Lechien">Jerome R. Lechien</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines, Paris Saclay University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines, Paris Saclay University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mannelli, Giuditta" sort="Mannelli, Giuditta" uniqKey="Mannelli G" first="Giuditta" last="Mannelli">Giuditta Mannelli</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental and Clinical Medicine, University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Molteni, Gabriele" sort="Molteni, Gabriele" uniqKey="Molteni G" first="Gabriele" last="Molteni">Gabriele Molteni</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Otorhinolaryngology Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University Hospital AOUI Borgo Trento, University of Verona, Verona, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Otorhinolaryngology Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University Hospital AOUI Borgo Trento, University of Verona, Verona</wicri:regionArea><wicri:noRegion>Verona</wicri:noRegion></affiliation></author><author><name sortKey="Cantarella, Giovanna" sort="Cantarella, Giovanna" uniqKey="Cantarella G" first="Giovanna" last="Cantarella">Giovanna Cantarella</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Sciences and Community Health, Milan University, Milan University, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Community Health, Milan University, Milan University, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Otolaryngology, Fondazione IRCCS Ca' Granda Policlinico Hospital, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology, Fondazione IRCCS Ca' Granda Policlinico Hospital, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Coppola, Nicola" sort="Coppola, Nicola" uniqKey="Coppola N" first="Nicola" last="Coppola">Nicola Coppola</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Costa, Giuseppe" sort="Costa, Giuseppe" uniqKey="Costa G" first="Giuseppe" last="Costa">Giuseppe Costa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Trecca, Eleonora M C" sort="Trecca, Eleonora M C" uniqKey="Trecca E" first="Eleonora M C" last="Trecca">Eleonora M C. Trecca</name><affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia</wicri:regionArea><wicri:noRegion>Foggia</wicri:noRegion></affiliation></author><author><name sortKey="Grillo, Calogero" sort="Grillo, Calogero" uniqKey="Grillo C" first="Calogero" last="Grillo">Calogero Grillo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="La Mantia, Ignazio" sort="La Mantia, Ignazio" uniqKey="La Mantia I" first="Ignazio" last="La Mantia">Ignazio La Mantia</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania</wicri:regionArea><wicri:noRegion>Catania</wicri:noRegion></affiliation></author><author><name sortKey="Chiesa Estomba, Carlos M" sort="Chiesa Estomba, Carlos M" uniqKey="Chiesa Estomba C" first="Carlos M" last="Chiesa-Estomba">Carlos M. Chiesa-Estomba</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Universitario Donostia, San Sebastian, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Universitario Donostia, San Sebastian</wicri:regionArea><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Vicini, Claudio" sort="Vicini, Claudio" uniqKey="Vicini C" first="Claudio" last="Vicini">Claudio Vicini</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Otolaryngology, University of Ferrara, Ferrara, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Otolaryngology, University of Ferrara, Ferrara</wicri:regionArea><wicri:noRegion>Ferrara</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì</wicri:regionArea><wicri:noRegion>Forlì</wicri:noRegion></affiliation></author><author><name sortKey="Saussez, Sven" sort="Saussez, Sven" uniqKey="Saussez S" first="Sven" last="Saussez">Sven Saussez</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Nacci, Andrea" sort="Nacci, Andrea" uniqKey="Nacci A" first="Andrea" last="Nacci">Andrea Nacci</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>ENT Audiology Phoniatric Unit, University of Pisa, Pisa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>ENT Audiology Phoniatric Unit, University of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Cammaroto, Giovanni" sort="Cammaroto, Giovanni" uniqKey="Cammaroto G" first="Giovanni" last="Cammaroto">Giovanni Cammaroto</name><affiliation wicri:level="3"><nlm:affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì</wicri:regionArea><wicri:noRegion>Forlì</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of medical virology</title><idno type="eISSN">1096-9071</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this study was to evaluate the clinical features of mild-to-moderate coronavirus disease 2019 (COVID-19) in a sample of Italian patients and to investigate the occurrence of smell and taste disorders. Infected individuals with suspected (clinical diagnosis) or laboratory-confirmed COVID-19 infection were recruited. Patients completed a survey-based questionnaire with the aim of assessing their epidemiological and clinical characteristics, general otorhinolaryngological symptoms, and smell and taste disorders. A total of 294 patients with mild-to-moderate COVID-19 completed the survey (147 females). The most prevalent general symptoms included fever, myalgia, cough, and headache. A total of 70.4% and 59.2% of patients reported smell and taste disorders, respectively. A significant association between the two above-mentioned disorders was found (rs: 0.412; P < .001). Smell disorders occurred before the other symptoms in 11.6% of patients and was not significantly associated with nasal obstruction or rhinorrhea. Interestingly, our statistical analysis did not show any significant difference, either for general symptoms or otorhinolaryngological features, between the clinical diagnosis group and the laboratory-confirmed diagnosis (polymerase chain reaction) group. The structural equation model confirmed significant standardized paths (P < .05) between general symptoms, comorbidities, and general otorhinolaryngological complaints in the absence of a significant correlation between these elements and smell and taste alterations. The prevalence of smell and taste disorders in mild-to-moderate Italian COVID-19 patients is significant both in suspected and laboratory-confirmed cases and reveals a strong correlation between these clinical signs regardless of the presence of general or otorhinolaryngological symptoms, such as nasal obstruction or rhinorrhea.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32710639</PMID><DateRevised><Year>2020</Year><Month>08</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1096-9071</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Jul</Month><Day>25</Day></PubDate></JournalIssue><Title>Journal of medical virology</Title><ISOAbbreviation>J. Med. Virol.</ISOAbbreviation></Journal><ArticleTitle>A structural equation model to examine the clinical features of mild-to-moderate COVID-19: A multicenter Italian study.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1002/jmv.26354</ELocationID><Abstract><AbstractText>The purpose of this study was to evaluate the clinical features of mild-to-moderate coronavirus disease 2019 (COVID-19) in a sample of Italian patients and to investigate the occurrence of smell and taste disorders. Infected individuals with suspected (clinical diagnosis) or laboratory-confirmed COVID-19 infection were recruited. Patients completed a survey-based questionnaire with the aim of assessing their epidemiological and clinical characteristics, general otorhinolaryngological symptoms, and smell and taste disorders. A total of 294 patients with mild-to-moderate COVID-19 completed the survey (147 females). The most prevalent general symptoms included fever, myalgia, cough, and headache. A total of 70.4% and 59.2% of patients reported smell and taste disorders, respectively. A significant association between the two above-mentioned disorders was found (rs: 0.412; P < .001). Smell disorders occurred before the other symptoms in 11.6% of patients and was not significantly associated with nasal obstruction or rhinorrhea. Interestingly, our statistical analysis did not show any significant difference, either for general symptoms or otorhinolaryngological features, between the clinical diagnosis group and the laboratory-confirmed diagnosis (polymerase chain reaction) group. The structural equation model confirmed significant standardized paths (P < .05) between general symptoms, comorbidities, and general otorhinolaryngological complaints in the absence of a significant correlation between these elements and smell and taste alterations. The prevalence of smell and taste disorders in mild-to-moderate Italian COVID-19 patients is significant both in suspected and laboratory-confirmed cases and reveals a strong correlation between these clinical signs regardless of the presence of general or otorhinolaryngological symptoms, such as nasal obstruction or rhinorrhea.</AbstractText><CopyrightInformation>© 2020 Wiley Periodicals LLC.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Barillari</LastName><ForeName>Maria Rosaria</ForeName><Initials>MR</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-5457-1509</Identifier><AffiliationInfo><Affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bastiani</LastName><ForeName>Luca</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>CNR Institute of Clinical Physiology, Pisa, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lechien</LastName><ForeName>Jerome R</ForeName><Initials>JR</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-0845-0845</Identifier><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines, Paris Saclay University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mannelli</LastName><ForeName>Giuditta</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Molteni</LastName><ForeName>Gabriele</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Otorhinolaryngology Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University Hospital AOUI Borgo Trento, University of Verona, Verona, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cantarella</LastName><ForeName>Giovanna</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Sciences and Community Health, Milan University, Milan University, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Otolaryngology, Fondazione IRCCS Ca' Granda Policlinico Hospital, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coppola</LastName><ForeName>Nicola</ForeName><Initials>N</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5897-4949</Identifier><AffiliationInfo><Affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Costa</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Mental and Physical Health and Preventive Medicine, "L. Vanvitelli" University, Naples, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trecca</LastName><ForeName>Eleonora M C</ForeName><Initials>EMC</Initials><AffiliationInfo><Affiliation>Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grillo</LastName><ForeName>Calogero</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>La Mantia</LastName><ForeName>Ignazio</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Medical Sciences, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chiesa-Estomba</LastName><ForeName>Carlos M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Universitario Donostia, San Sebastian, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vicini</LastName><ForeName>Claudio</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Unit of Otolaryngology, University of Ferrara, Ferrara, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saussez</LastName><ForeName>Sven</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nacci</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>ENT Audiology Phoniatric Unit, University of Pisa, Pisa, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cammaroto</LastName><ForeName>Giovanni</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>COVID-19 Task Force of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Head-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Pierantoni Hospital, Azienda USL Della Romagna, Forlì, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>07</Month><Day>25</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Med Virol</MedlineTA><NlmUniqueID>7705876</NlmUniqueID><ISSNLinking>0146-6615</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">ENT</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword><Keyword MajorTopicYN="N">anosmia</Keyword><Keyword MajorTopicYN="N">coronavirus</Keyword><Keyword MajorTopicYN="N">smell and taste</Keyword><Keyword MajorTopicYN="N">structural equation model</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>07</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>07</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>7</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>7</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>7</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32710639</ArticleId><ArticleId IdType="doi">10.1002/jmv.26354</ArticleId></ArticleIdList><ReferenceList><Title>REFERENCES</Title><Reference><Citation>Centers for Disease Control and Prevention (CDC). 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N Engl J Med. 2020;382(13):1199-1207. https://doi.org/10.1056/NEJMoa2001316</Citation></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Belgique</li><li>Espagne</li><li>France</li><li>Italie</li></country><region><li>Lombardie</li><li>Région de Bruxelles-Capitale</li><li>Toscane</li><li>Île-de-France</li></region><settlement><li>Bruxelles</li><li>Milan</li><li>Paris</li><li>Pise</li></settlement><orgName><li>Université de Pise</li><li>Université libre de Bruxelles</li></orgName></list><tree><country name="Italie"><noRegion><name sortKey="Barillari, Maria Rosaria" sort="Barillari, Maria Rosaria" uniqKey="Barillari M" first="Maria Rosaria" last="Barillari">Maria Rosaria Barillari</name></noRegion><name sortKey="Bastiani, Luca" sort="Bastiani, Luca" uniqKey="Bastiani L" first="Luca" last="Bastiani">Luca Bastiani</name><name sortKey="Cammaroto, Giovanni" sort="Cammaroto, Giovanni" uniqKey="Cammaroto G" first="Giovanni" last="Cammaroto">Giovanni Cammaroto</name><name sortKey="Cantarella, Giovanna" sort="Cantarella, Giovanna" uniqKey="Cantarella G" first="Giovanna" last="Cantarella">Giovanna Cantarella</name><name sortKey="Cantarella, Giovanna" sort="Cantarella, Giovanna" uniqKey="Cantarella G" first="Giovanna" last="Cantarella">Giovanna Cantarella</name><name sortKey="Coppola, Nicola" sort="Coppola, Nicola" uniqKey="Coppola N" first="Nicola" last="Coppola">Nicola Coppola</name><name sortKey="Costa, Giuseppe" sort="Costa, Giuseppe" uniqKey="Costa G" first="Giuseppe" last="Costa">Giuseppe Costa</name><name sortKey="Grillo, Calogero" sort="Grillo, Calogero" uniqKey="Grillo C" first="Calogero" last="Grillo">Calogero Grillo</name><name sortKey="La Mantia, Ignazio" sort="La Mantia, Ignazio" uniqKey="La Mantia I" first="Ignazio" last="La Mantia">Ignazio La Mantia</name><name sortKey="Mannelli, Giuditta" sort="Mannelli, Giuditta" uniqKey="Mannelli G" first="Giuditta" last="Mannelli">Giuditta Mannelli</name><name sortKey="Molteni, Gabriele" sort="Molteni, Gabriele" uniqKey="Molteni G" first="Gabriele" last="Molteni">Gabriele Molteni</name><name sortKey="Nacci, Andrea" sort="Nacci, Andrea" uniqKey="Nacci A" first="Andrea" last="Nacci">Andrea Nacci</name><name sortKey="Trecca, Eleonora M C" sort="Trecca, Eleonora M C" uniqKey="Trecca E" first="Eleonora M C" last="Trecca">Eleonora M C. Trecca</name><name sortKey="Vicini, Claudio" sort="Vicini, Claudio" uniqKey="Vicini C" first="Claudio" last="Vicini">Claudio Vicini</name><name sortKey="Vicini, Claudio" sort="Vicini, Claudio" uniqKey="Vicini C" first="Claudio" last="Vicini">Claudio Vicini</name></country><country name="France"><region name="Île-de-France"><name sortKey="Barillari, Maria Rosaria" sort="Barillari, Maria Rosaria" uniqKey="Barillari M" first="Maria Rosaria" last="Barillari">Maria Rosaria Barillari</name></region><name sortKey="Cammaroto, Giovanni" sort="Cammaroto, Giovanni" uniqKey="Cammaroto G" first="Giovanni" last="Cammaroto">Giovanni Cammaroto</name><name sortKey="Cantarella, Giovanna" sort="Cantarella, Giovanna" uniqKey="Cantarella G" first="Giovanna" last="Cantarella">Giovanna Cantarella</name><name sortKey="Chiesa Estomba, Carlos M" sort="Chiesa Estomba, Carlos M" uniqKey="Chiesa Estomba C" first="Carlos M" last="Chiesa-Estomba">Carlos M. Chiesa-Estomba</name><name sortKey="Lechien, Jerome R" sort="Lechien, Jerome R" uniqKey="Lechien J" first="Jerome R" last="Lechien">Jerome R. Lechien</name><name sortKey="Lechien, Jerome R" sort="Lechien, Jerome R" uniqKey="Lechien J" first="Jerome R" last="Lechien">Jerome R. Lechien</name><name sortKey="Mannelli, Giuditta" sort="Mannelli, Giuditta" uniqKey="Mannelli G" first="Giuditta" last="Mannelli">Giuditta Mannelli</name><name sortKey="Molteni, Gabriele" sort="Molteni, Gabriele" uniqKey="Molteni G" first="Gabriele" last="Molteni">Gabriele Molteni</name><name sortKey="Nacci, Andrea" sort="Nacci, Andrea" uniqKey="Nacci A" first="Andrea" last="Nacci">Andrea Nacci</name><name sortKey="Saussez, Sven" sort="Saussez, Sven" uniqKey="Saussez S" first="Sven" last="Saussez">Sven Saussez</name></country><country name="Espagne"><noRegion><name sortKey="Chiesa Estomba, Carlos M" sort="Chiesa Estomba, Carlos M" uniqKey="Chiesa Estomba C" first="Carlos M" last="Chiesa-Estomba">Carlos M. Chiesa-Estomba</name></noRegion></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Saussez, Sven" sort="Saussez, Sven" uniqKey="Saussez S" first="Sven" last="Saussez">Sven Saussez</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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